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Molecular Pathology of
Gallbladder Cancer
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Affected Protein Pathway Sub-Type Ethnicity Stage Frequency (%) Gene Amplification Activating Mutation Inactivating Mutation Deletion Promoter Hypermethylation Comment  
KRAS Ras Signal Transduction Pathway
20%
p16 31%
p53 p53 Tumor Suppressor Pathway
36%
Pi3-kinase PI3-Kinase Signaling
Gallbladder Carcinomas 4%

See Clinical Trials in in the TTC Database
CANCER.GOV PDQ® - Standard Treatments for Gallbladder Cancer